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Evaluations for IgG4-RD require the coordination of multiple medical specialties and a combination of diagnostic tests1,2

Testing for IgG4-RD includes3

Test

Area of Focus

Serology

  • Levels of IgG, C3, C4, and other potential biomarkers

Imaging

  • MRI and CT scans of affected organs

Tissue biopsy

  • Lymphoplasmacytic tissue inflammation

IgG4+

  • IgG plasma ratios and storiform fibroses

Due to the variety of organs affected by IgG4-RD, multiple specialties must often play a role in its management1,2
  • promo-1

    Rheumatologists

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IgG4-RD, immunoglobulin G4-related disease.

LEARN ABOUT ADDITIONAL RESOURCES
  • References:

    1. Wallace ZS, Zhang Y, Perugino CA, et al. Ann Rheum Dis. 2019;78(3):406-412. doi:10.1136/annrheumdis-2018-214603 2. Alliance for Patient Access. 2021. https://admin.allianceforpatientaccess.org/wp-content/uploads/2021/12/AfPA_In-Their-Own-Voices_IgG4-RD-Report_Dec-2021.pdf 3. Umehara H, Okazaki K, Kawa S, et al. Mod Rheumatol. 2021;31(3):529-533. doi:10.1080/14397595.2020.1859710